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2'-Fluoro-iBu-G Phosphoramidite, standard grade, 20-400 finish bottle
2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis.
Marca: Thermo Scientific 27-1607-09
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Descripción
Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.
Features:
- Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- Molecular formula—C44H53FN7O8P
- Base—G
- Base Protection—iBu
- Formula weight—857.4 g/mol
- CAS number—144089-97-4
- HPLC purity—>98%
- 31P NMR purity—≥98%
Especificaciones
| Polvo | |
| 2in-Fluoro-iBu-G CEP | |
| Guanosina (G) | |
| Temperatura ambiente | |
| 0.25 g | |
| Estándar |
| Sintetizadores Expedite | |
| Store in freezer (at or below -20°C). | |
| 2in-Fluoro modified | |
| 98% | |
| Fosforamidita | |
| ARN |
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Título del producto
2'-Fluoro-iBu-G Phosphoramidite, standard grade, 20-400 finish bottle > 0.25 g
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.
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