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  7. Tetrafluoroborato de 2-Succinimido-1,1,3,3-tetrametiluronio, 98 %, Thermo Scientific Chemicals

Tetrafluoroborato de 2-Succinimido-1,1,3,3-tetrametiluronio, 98 %, Thermo Scientific Chemicals

Catalog Number 11373127
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Cantidad:
5 g
25 g
This item is not returnable. View return policy
105832-38-0
C9H16BF4N3O3
301.05
MFCD00077875
YEBLHMRPZHNTEK-UHFFFAOYSA-N
tstu, o-n-succinimidyl-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-2,5-dioxopyrrolidin-1-yl-1,1,3,3-tetramethylisouronium tetrafluoroborate, 2-succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl-uronium tetrafluoroborate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl uronium bf4, pubchem12781
9857522
[dimetilamino-(2,5-dioxopirrolidina-1-il)oximetilideno]-dimetilazanio;tetrafluoroborato
F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C
This item is not returnable. View return policy
105832-38-0
C9H16BF4N3O3
301.05
MFCD00077875
YEBLHMRPZHNTEK-UHFFFAOYSA-N
tstu, o-n-succinimidyl-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-2,5-dioxopyrrolidin-1-yl-1,1,3,3-tetramethylisouronium tetrafluoroborate, 2-succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl-uronium tetrafluoroborate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium tetrafluoroborate, o-n-succinimidyl-n,n,n',n'-tetramethyl uronium bf4, pubchem12781
9857522
[dimetilamino-(2,5-dioxopirrolidina-1-il)oximetilideno]-dimetilazanio;tetrafluoroborato
F[B-](F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C

Description

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
El tetrafluoroborato 2-Succinimido-1,1,3,3-tetrametiluronio (TSTU) actúa como un eficaz agente de acoplamiento mediante la rápida activación de los ácidos carboxílicos para formar ésteres activos de N-succinimidilo, que reaccionan con aminas primarias para formar carboxamidas. Es eficaz incluso en agua. TSTU es selectivo con las aminas en presencia de grupo alcohólico. Se emplea como un regente de acoplamiento en la síntesis de péptidos. Con alfa-aminoácidos protegidos con amina, provoca un acoplamiento sin epimerización significativa. Es útil para la vinculación de moléculas de sensor con grupos amino a AFM (microscopio de fuerza atómica) amino-funcionalizados.

Solubilidad
Soluble en acetonitrilo, DMF, cloroformo, diclorormetano y acetonitrilo.

Notas
Sensible a la humedad, Incompatible con agentes oxidantes fuertes.
TRUSTED_SUSTAINABILITY
Nombre del producto químico o material 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate
Punto de fusión 195°C to 200°C
Cantidad 5 g
Sensibilidad Moisture sensitive
Información de solubilidad Soluble in acetonitrile,DMF,chloroform,dichlorormethane and acetonitrile.
Formula Weight (peso de la fórmula) 301.05
Porcentaje de pureza 98%

RUO – Research Use Only

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