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Tocris Bioscience™ A66
Potent and selective PI 3-kinase p110α inhibitor
Marca: Tocris Bioscience™ 5595/10
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Descripción
A66 is a potent and selective PI 3-kinase p110α inhibitor (IC50 = 32 nM). Exhibits >100-fold selectivity for p110α over other PI 3-kinase isoforms. Inhibits Akt signaling and tumor growth in SK-OV-3 xenografts in mice.Especificaciones
| (2S)-N1-[2-(1,1-Dimethylethyl)-4′-methyl[4,5′-bithiazol]-2′-yl]-1,2-pyrrolidinedicarboxamide | |
| 1166227-08-2 | |
| 10 mg |