Invitrogen™ Human ABL1 [F317L], GST Tag Recombinant Protein

This ABL1 F317L Recombinant Human Protein (27-end) was expressed in insect cells.

Marca: Invitrogen™ A33475

Código de producto. 15940403

Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

Este artículo no se puede devolver. Vea la política de devoluciones

Descripción

This ABL1 F317L recombinant human protein (27–end) was expressed in insect cells
ABL1 cytoplasmic tyrosine kinase protooncogene encodes a cytoplasmic and nuclear kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene
Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia
The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1
ABL1 F317L recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
Validated for use with the Z'-LYTE™ assay
Available in multiple pack sizes for convenient use

Especificaciones

Para utilizar con (aplicación)	Kinase Assay
Cantidad	10 μg
Longitud de la proteína	aa 27 - end
Recombinante	Recombinant
Contenido y almacenamiento	Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Sistema de expresión	Baculovirus
Forma de proteína	Recombinant, Active, Mutant

Sugerencias de productos

Descripción