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ADAMTS13 Recombinant Rabbit Monoclonal Antibody (7B2Z8), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen MA542805
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Descripción
Positive test controls include: Mouse liver, Mouse spleen, Mouse plasma, Rat plasma. Immunogen sequence: LSPGAPLKGR PPSPGFQRQR QRQRRAAGGI LHLELLVAVG PDVFQAHQED TERYVLTNLN IGAELLRDPS LGAQFRVHLV KMVILTEPEG APNITANLTS S
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.Especificaciones
ADAMTS13 | |
Recombinant Monoclonal | |
2 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q769J6, Q76LX8 | |
ADAMTS13 | |
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ADAMTS13 (Q76LX8). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
7B2Z8 | |
Unconjugated | |
ADAMTS13 | |
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 13; A disintegrin and metalloproteinase with thrombospondin motifs 13-like; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 13; ADAM metallopeptidase with thrombospondin type 1 motif, 13; ADAMs; ADAM-TS 13; ADAMTS13; ADAM-TS13; ADAMTS-13; C9orf8; Gm710; LOC102554393; metalloendopeptidases; UNQ6102/PRO20085; von Willebrand factor-cleaving protease; vWF-cleaving protease; VWFCP; vWF-CP; vWF-CP mRNA for von Willebrand factor-cleaving | |
Rabbit | |
Affinity Chromatography | |
RUO | |
102554393, 11093, 279028 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |