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AKT1 Monoclonal Antibody (3A3), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA515591
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Descripción
MA5-15591 targets AKT1 in indirect ELISA, WB applications and shows reactivity with Human, mouse, and Non-human primate samples. The MA5-15591 immunogen is purified recombinant fragment of human AKT1 expressed in E. Coli. . MA5-15591 detects AKT1 which has a predicted molecular weight of approximately 56kDa.
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
Especificaciones
| AKT1 | |
| Monoclonal | |
| 1 mg/mL | |
| ascites with 0.03% sodium azide | |
| P31749, P31750 | |
| AKT1 | |
| Purified recombinant fragment of human AKT1 expressed in E. Coli. | |
| RUO | |
| 11651, 207 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Western Blot | |
| 3A3 | |
| Unconjugated | |
| AKT1 | |
| Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human, Mouse, Non-human Primate | |
| Antibody | |
| IgG1 |