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Alkaline Phosphatase/ALPP Antibody (ALP/870) - IHC-Prediluted, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-48092
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Descripción
Alkaline Phosphatase/ALPP Monoclonal specifically detects Alkaline Phosphatase/ALPP in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Especificaciones
| Alkaline Phosphatase/ALPP | |
| Monoclonal | |
| Unconjugated | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| ALPP | |
| Recombinant full-length human Alkaline Phosphatase/ALPP protein (Uniprot: P05187 ) | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. | |
| Store at 4C. | |
| IgG2b κ |
| Immunohistochemistry (Paraffin) | |
| ALP/870 | |
| Immunohistochemistry-Paraffin | |
| Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental (Regan isozyme), alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, EC 3.1.3.1, FLJ61142, glycerophosphatase, PALP, Placental alkaline phosphatase 1, PLAP, PLAP-1, Regan isozyme | |
| Mouse | |
| 70 kDa | |
| 7 mL | |
| Cancer, Embryonic Stem Cell Markers, Ovarian Carcinoma Cell Markers, Stem Cell Markers | |
| 250 | |
| Human | |
| Purified |
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