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alpha Actinin 3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA527862
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Descripción
Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, JC, PC-12. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (94%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele.
Especificaciones
| alpha Actinin 3 | |
| Polyclonal | |
| Unconjugated | |
| Actn3 | |
| actinin alpha 3; actinin alpha 3 (gene/pseudogene); Actinin alpha3; actinin, alpha 3; Actinin-alpha3; ACTN3; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 3; alpha-Actinin3; Alpha-actinin-3; alphaActinin-3; F-actin cross-linking protein | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 11474, 171009, 89 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| O88990, Q08043 | |
| Actn3 | |
| Recombinant fragment corresponding to a region within amino acids 1 and 363 of Human alpha Actinin 3 | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |