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Invitrogen™ AMOTL2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA566549
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Descripción
Immunogen sequence: PHPAALGHGPL SSLSPPAVEG PVSAQASSAT SGSAHLAQME AVLRENARLQ RDNERLQREL ESSAEKAGRI EKLESEIQRL SEAHESLTRA SSKRE Highest antigen sequence identity to the following orthologs - mouse 84%, rat 82%.
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Especificaciones
| AMOTL2 | |
| Polyclonal | |
| Unconjugated | |
| AMOTL2 | |
| AMOTL2; angiomotin like 2; angiomotin-like 2; angiomotin-like protein 2; AW549739; C79691; KIAA0989; LCCP; Leman coiled-coil protein; MASCOT; mKIAA0989 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 51421 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9Y2J4 | |
| AMOTL2 | |
| Recombinant Human AMOTL2. Recombinant protein control fragment (Product #RP-107211). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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