Apolipoprotein A4 Monoclonal Antibody (1D4C11), Invitrogen™

Descripción

MA5-15483 targets APOA4 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15483 immunogen is purified recombinant fragment of APOA4 (aa21-396) expressed in E. Coli.<br>. MA5-15483 detects APOA4 which has a predicted molecular weight of approximately 45kDa.

Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is an O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but evidence from several in vitro studies indicate that this apolipoprotein is involved in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.