CD16/CD32 Rat anti-Mouse, Unlabeled, Clone: 2.4G2, BD

Descripción

The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc γ III and Fc γ II receptors. It has also been reported to bind the Fc γ I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc γ III and Fc γ II, and possibly Fc γ I, receptors in vitro and in vivo . CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.