missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ERK (pan ERK) Mouse, Unlabeled, Clone: 16, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 610124
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. A myriad of proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK1 may be observable migrating at 44kDa and ERK2 at 42kDa in addition to a 54kDa ERK and a MAP kinase in the 90kDa range.
Host Species: Mouse
Clone: 16
Isotype: IgG2a
Species Reactivity: Mouse
Immunogen: Rat ERK2 aa. 219-358
Formula Weight [Chemical]: 42-85kDa
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Especificaciones
| ERK (pan ERK) | |
| Monoclonal | |
| 250μg/mL | |
| Extracellular signal Regulated Kinases | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at -20°C. |
| Western Blot | |
| 16 | |
| Unconjugated | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Rat ERK2 aa. 219-358 | |
| 150 μg | |
| Cell Biology | |
| Canine, Chicken, Frog, Human, Mouse, Rat | |
| IgG2a |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
For Research Use Only.
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido