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FEN1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA527518
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Descripción
Recommended positive controls: HepG2, NIH-3T3, JC, BCL-1, Raw264.7, PC-12. Predicted reactivity: Mouse (96%), Rat (95%), Chicken (81%), Sheep (94%), Rhesus Monkey (98%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
Especificaciones
| FEN1 | |
| Polyclonal | |
| Unconjugated | |
| FEN1 | |
| AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 14156, 2237, 84490 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Proximity Ligation Assay, Western Blot | |
| 0.72 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| P39748, P39749, Q5XIP6 | |
| FEN1 | |
| Recombinant fragment corresponding to a region within amino acids 169 and 380 of Human FEN1 | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Título del producto
FEN1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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