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Fetal Hemoglobin Mouse anti-Human, Unlabeled, Clone: 2D12, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 551796
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Descripción
Reacts with fetal hemoglobin (HbF), a form of hemoglobin present during fetal development. HbF resembles adult hemoglobin (HbA) in possessing two alpha chains but differs in possessing two gamma instead of two beta chains. In normal adults, synthesis of HbF does persist at very low levels (<1% of total Hb) and is restricted to a small population of erythrocytes called F cells. Hemoglobin F-expressing erythrocytes are normally seen during pregnancy. An increase in the expression of fetal hemoglobin in adult peripheral red blood cells is a common feature
in the genetic disorders of hemoglobin, sickle-cell disease (SCD) and beta thalassemia. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Mouse
Clone: 2D12
Isotype: IgG1 κ
Species Reactivity: Human
Flow Cytometry, Intracellular Staining
Especificaciones
| Fetal Hemoglobin | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 2D12 | |
| Unconjugated | |
| Mouse | |
| 0.1 mg | |
| Cell Biology | |
| Human | |
| IgG1 κ |
For Research Use Only.