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FGFR4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA514656
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Descripción
FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
Especificaciones
| FGFR4 | |
| Polyclonal | |
| Unconjugated | |
| Fgfr4 | |
| CD334; CTLA-2-beta protein; FGF Receptor 4; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 2264 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide | |
| P22455 | |
| Fgfr4 | |
| KLH conjugated synthetic peptide between 24-55 amino acids from the N-terminal region of human FGFR4 | |
| 200 μL | |
| Primary | |
| Human | |
| Antibody | |
| Ig |