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MMP13 Monoclonal Antibody (VIIIA2), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA514238
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Descripción
MA5-14238 targets MMP-13 (Collagenase-3) in IHC (P) and IP applications and shows reactivity with Human, mouse, and Rabbit samples. The MA5-14238 immunogen is human recombinant collagenase-3 protein.
MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
Especificaciones
| MMP13 | |
| Monoclonal | |
| 0.4 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P33435, P45452 | |
| MMP13 | |
| Human recombinant collagenase-3 protein | |
| 500 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 κ |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| VIIIA2 | |
| Unconjugated | |
| MMP13 | |
| cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13 | |
| Mouse | |
| Protein G | |
| RUO | |
| 17386, 4322 | |
| 4° C | |
| Liquid |
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