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NeuroD1 Mouse, Alexa Fluor 647, Clone: R8-294, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 563566
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Descripción
The R8-294 monoclonal antibody specifically binds to Neurogenic differentiation factor 1 (NeuroD1). NeuroD1 is a basic helix-loop-helix (bHLH) transcription factor that is also known as BHLHA3, Beta-cell E-box transactivator 2, BETA2 and NeuroD. NeuroD1 interacts with other bHLH proteins and binds the insulin E-box sequence to regulate pancreatic islet cell development. It also plays a key role in central nervous system (CNS) and sensory nervous system neuron development.Specifically, it is required for the terminal differentiation of neurons during late stages of neurogenesis in the CNS (cerebral cortex, hippocampus, and cerebellum) and the sensory nervous system (eye, inner ear, and olfactory system). During antibody development, the purified R8-294 monoclonal antibody was found to detect NeuroD1 by western blot and indirect immunofluorescent staining followed by flow cytometric analysis or imaging analysis.
Especificaciones
| NeuroD1 | |
| Monoclonal | |
| Alexa Fluor 647 | |
| Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
| Human NeuroD1 Recombinant Protein | |
| 50 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| R8-294 | |
| Class A basic helix-loop-helix protein 3, bHLHa3, BETA2, NeuroD | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human, Mouse | |
| IgG1 κ |