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Phospho-p300 (Ser89) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA512652
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Descripción
This antibody is predicted to react with mouse based on sequence homology.
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Especificaciones
| Phospho-p300 (Ser89) | |
| Polyclonal | |
| Unconjugated | |
| EP300 | |
| A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2 | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 2033 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Dot Blot, Immunohistochemistry (Paraffin) | |
| 0.45 mg/mL | |
| PBS with 0.09% sodium azide | |
| Q09472 | |
| EP300 | |
| KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S89 of human EP300 | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |