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Invitrogen™ APC15 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA546112
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Descripción
Peptide sequence: EETELQQQEQ QHQAWLQSIA EKDNNLVPIG KPASEHYDDE EEEDDEDDED Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 90%.
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Especificaciones
| APC15 | |
| Polyclonal | |
| Unconjugated | |
| Anapc15 | |
| 3200002M19Rik; 6330414C15Rik; Anapc15; anaphase promoting complex subunit 15; anaphase prompoting complex C subunit 15; anaphase-promoting complex subunit 15; APC15; C11orf51; C15H11orf51; C21H11orf51; HSPC020; hypothetical protein LOC505356; protein HSPC020 homolog; RGD1311634; uncharacterized protein C11orf51 homolog; Unknown (protein for MGC:153425); zgc:153425 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 25906 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| P60006 | |
| Anapc15 | |
| Synthetic peptide directed towards the N-terminal of human ANAPC15 (aa 26-75). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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