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Beta-Tubulin III Mouse, anti-Human, Unconjugated, Clone: AA10, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60100.1
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Descripción
- The AA10 antibody reacts with beta-tubulin III, an ∼50 - 55 kDa structural protein that is a constituent of tubulin
- Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha and beta tubulin subunits
- The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types
- Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation
- It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells
- The AA10 antibody is expected to recognize all mammalian homologs of beta-tubulin III
Especificaciones
| Beta-Tubulin III | |
| Monoclonal | |
| Unconjugated | |
| 25 μg | |
| Human, Rat, Mouse | |
| Neural Cells, PSC-Derived, Neurons |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| AA10 | |
| Mouse | |
| Primary | |
| IgG2a κ |
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