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BMI1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 10832-1-AP-20UL
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Descripción
The antibody 10832-1-AP detected proteins of 45-48 kDa, which may include phosphorylated isoforms of the protein.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.Especificaciones
| BMI1 | |
| Polyclonal | |
| Unconjugated | |
| BMI1 | |
| BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 12151, 648 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot | |
| 0.27 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P25916, P35226 | |
| BMI1 | |
| BMI1 Fusion Protein Ag1286 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |