CA125 Monoclonal Antibody (Ov185:1), Invitrogen™

Descripción

MA5-11579 targets CA-125 in IHC (P) applications and shows reactivity with Human samples. The MA5-11579 immunogen is partially purified mucin fraction from a pool of cancer tissue from patients with epithelial ovarian cancer.

CA 125 determinant is present on a high molecular weight, mucin like glycoprotein of high molecular weight. CA 125 has been found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium and peritoneum. In adult tissues, epithelial cells of fallopian tube, endometrium and endocervix; pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland and mammary gland. It is also found in mesothelial cell lining of pleura, pericardium and peritoneum. It is found in ovarian tumors of serous, endometrioid or clear cell types and adenocarcinomas of mullerian type.