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Invitrogen™ CD105 Monoclonal Antibody (3A9)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA517041
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Descripción
MA5-17041 targets CD105 in indirect ELISA, FACS, ICC, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-17041 immunogen is purified recombinant fragment of human CD105 expressed in E. Coli. MA5-17041 detects CD105 which has a predicted molecular weight of approximately 71kDa.
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Especificaciones
| CD105 | |
| Monoclonal | |
| Conc. Not Determined | |
| Ascites with 0.03% sodium azide | |
| P17813 | |
| ENG | |
| Purified recombinant fragment of human CD105 expressed in E. Coli. | |
| RUO | |
| 2022 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 3A9 | |
| Unconjugated | |
| ENG | |
| AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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