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CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), PE, Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen A15779
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Descripción
Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.
Especificaciones
| CD264 (TRAIL-R4) | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 0.2% BSA and 15mM sodium azide | |
| Q9UBN6 | |
| TNFRSF10D | |
| Human CD264 | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry | |
| TRAIL-R4-01 | |
| PE | |
| TNFRSF10D | |
| CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, TRAIL receptor 4 | |
| Mouse | |
| Purified | |
| RUO | |
| 8793 | |
| 4° C | |
| Liquid |
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