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CD7 Antibody (T3-3A1), Alexa Fluor™ 647, Novus Biologicals™
Mouse Monoclonal Antibody
Marca: Novus Biologicals NBP2-54901AF647
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Descripción
CD7 Monoclonal specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.
Especificaciones
| CD7 | |
| Monoclonal | |
| Alexa Fluor 647 | |
| 50mM Sodium Borate with 0.05% Sodium Azide | |
| CD7 | |
| Human T cells | |
| 0.1 mL | |
| Cytokine Research, Signal Transduction | |
| Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. | |
| Store at 4°C in the dark. |
| Flow Cytometry, Immunofluorescence | |
| T3-3A1 | |
| Flow Cytometry, Immunofluorescence | |
| CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein | |
| Mouse | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Human | |
| IgG1 κ |
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