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Crk Monoclonal Antibody (3G11C1), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA515891
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Descripción
MA5-15891 targets CRK in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15891 immunogen is purified recombinant fragment of human CRK expressed in E. Coli. . MA5-15891 detects CRK which has a predicted molecular weight of approximately 42kDa.
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Especificaciones
| Crk | |
| Monoclonal | |
| Conc. Not Determined | |
| ascites with 0.03% sodium azide | |
| P46108, P47811, Q16539, Q64010 | |
| Crk, Mapk14 | |
| Purified recombinant fragment of human CRK expressed in E. Coli. | |
| RUO | |
| 12928, 1398, 1432, 26416 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot | |
| 3G11C1 | |
| Unconjugated | |
| Mapk14 | |
| Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; c-Crk; CRK; CRK proto-oncogene, adaptor protein; CRK1; Crk3; Crk-I; CRKII; Crk-II; CrkIII; Crk-III; Crko; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; CSBP2; CSPB1; CT-10 related kinase 3; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Exip; Hog; I79_016605; MAP kinase 14; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38 alpha; MAPK 14; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen-activated protein kinase 14; mitogen-activated protein kinase 14A; mitogen-activated protein kinase p38 alpha; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38a; p38ALPHA; p38-alpha; p38alpha Exip; p38Hog; p38MAPK; PRKM14; PRKM15; Prot | |
| Mouse | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2b |