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ACROBiosystems Cynomolgus LAG-3 / CD223 Protein, Fc Tag
Marca: ACROBiosystems LA3-C5252-1MG
Detalles adicionales : Peso : 0.00001kg
Descripción
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.0 kDa. The protein migrates as 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
XP_005570011.1 | |
1 mg | |
Ala 18 - His 449 | |
LAG3,CD223,FDC | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>85% as determined by SDS-PAGE |
73.0 kDa | |
Cynomolgus LAG-3, Fc Tag (LA3-C5252) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - His 449 (Accession # XP_005570011.1). | |
-20°C | |
LAG-3 | |
Cynomolgus Monkey | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |