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EDEM1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA556191
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Descripción
Immunogen sequence: SLEKYTKVKC GYATLHHVID KSTEDRMESF FLSETCKYLY LLFDEDNPVH KSGTRYMFTT EGHIVSVDEH LRELPWKEFF SEEGGQDQGG KSVHRPKPHE LKVINSSSNC NRVPDE Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
Especificaciones
| EDEM1 | |
| Polyclonal | |
| Unconjugated | |
| EDEM1 | |
| A130059K23Rik; EDEM; EDEM1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1; KIAA0212; mKIAA0212; RGD1563633 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9695 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q92611 | |
| EDEM1 | |
| Recombinant protein corresponding to Human EDEM1 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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Título del producto
Research Use Only
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