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EDEM1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA556191
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Descripción
Immunogen sequence: SLEKYTKVKC GYATLHHVID KSTEDRMESF FLSETCKYLY LLFDEDNPVH KSGTRYMFTT EGHIVSVDEH LRELPWKEFF SEEGGQDQGG KSVHRPKPHE LKVINSSSNC NRVPDE Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.
EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.Especificaciones
EDEM1 | |
Polyclonal | |
Unconjugated | |
EDEM1 | |
A130059K23Rik; EDEM; EDEM1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1; KIAA0212; mKIAA0212; RGD1563633 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9695 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q92611 | |
EDEM1 | |
Recombinant protein corresponding to Human EDEM1 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only