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Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Antibody (A7L6), Novus Biologicals™
Rat Monoclonal Antibody has been used in 1 publication
Marca: Bio-Techne NBP2-44448-0.1MG
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Descripción
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Endorepellin/Perlecan/Heparan Sulfate Proteoglycan Monoclonal specifically detects Endorepellin/Perlecan/Heparan Sulfate Proteoglycan in Human, Mouse, Porcine, Bovine, Fish, Monkey samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunofluorescence.Especificaciones
| Endorepellin/Perlecan/Heparan Sulfate Proteoglycan | |
| Monoclonal | |
| 0.2mg/mL | |
| Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml | |
| P98160 | |
| HSPG2 | |
| Murine EHS laminin preparation | |
| 0.1 mg | |
| Primary | |
| This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. | |
| Store at 4C. | |
| IgG2a κ |
| Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence | |
| A7L6 | |
| Unconjugated | |
| 10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
| basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1 | |
| Rat | |
| Protein A or G purified | |
| RUO | |
| 3339 | |
| Human, Mouse, Porcine, Fish, Monkey | |
| Purified |
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For Research Use Only
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