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Tocris Bioscience™ ERGi-USU
Rio2 kinase (RIOK2) inhibitor
Marca: Tocris Bioscience™ 6632/50
Detalles adicionales : Peso : 0.00970kg
Descripción
ERGi-USU is a high affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM). Exhibits >6-fold selectivity for RIOK2 over a panel of 456 kinases. Inhibits ERG protein and potently inhibits growth of ERG-positive VCaP prostate cancer cells in vitro (IC50 = 169 nM) but not ERG-negative cell lines. Also inhibits growth of VCaP xenografts in mice.Especificaciones
| 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol | |
| 50 mg | |
| 255.3 |
| 1147-56-4 | |
| C13H9N3OS | |
| 99% |