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Fasudil hydrochloride, Tocris Bioscience™
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Cantidad:
10 mg
50 mg
Descripción
Fasudil hydrochloride is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Fasudil suppresses MMP-2 expression and induces apoptosis in glioblastoma cells in vivo. Fasudil is a Ca2+ antagonist, vasodilator and inhibits proliferation of vascular smooth muscle cells. Fasudil binds to α-synuclein to reduce aggregate formation in cellular models of Parkinson's disease, also displays neuroprotective properties and increases survival of dopaminergic neurons in vivo.
Especificaciones
Nombre del producto químico o material | Fasudil hydrochloride |
Cantidad | 10 mg |
Formula Weight (peso de la fórmula) | 327.83 |
Porcentaje de pureza | >98% |
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