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FGFR4 Monoclonal Antibody (19H3), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA518084
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Descripción
This target has a predicted molecular weight of 88 kDa. Actual Western blot results show a band at 105 kDa.
FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.Especificaciones
FGFR4 | |
Monoclonal | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
P22455 | |
Fgfr4 | |
Cytoplasmic domain of human FGFR4 fused to maltose binding protein | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunoprecipitation, Western Blot | |
19H3 | |
Unconjugated | |
Fgfr4 | |
CD334; CTLA-2-beta protein; FGF Receptor 4; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase | |
Mouse | |
Protein A | |
RUO | |
2264 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |