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GADD45A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA512383
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Descripción
This antibody is predicted to react with bovine based on sequence homology.
GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.
Especificaciones
| GADD45A | |
| Polyclonal | |
| Unconjugated | |
| GADD45A | |
| AA545191; DDIT 1; DDIT1; DDIT-1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; DNA-damage inducible transcript 1; DNA-damage-inducible transcript 1; GADD45; GADD45A; Gadd45alpha; growth arrest and DNA damage inducible alpha; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA-damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible, alpha | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 1647 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 2 mg/mL | |
| PBS with 0.09% sodium azide | |
| P24522 | |
| GADD45A | |
| KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GADD45A | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |