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Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Marca: Thermo Scientific™ K1716
Descripción
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ M3-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of Carbachol. In addition, GeneBLAzer™ M3-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The M3 receptor is localized in smooth muscle, exocrine glands, and the central nervous system. M3 has been implicated in autoimmune and neurological disorders.
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Especificaciones
NM_000740.2 | |
Células divisoras | |
Fluorescente | |
M3 | |
Origen del clon unicelular | |
2 x 106 células | |
M3 | |
CHO-K1 | |
GPCR |
Gen informador de beta lactamasa a base de células | |
Contenido: Células K1716 GeneBLAzer™ M3-NFAT-bla CHO-K1 (El kit de carga LiveBLAzer™-FRET B⁄G, la solución D y otros materiales se solicitan por separado; consulte el protocolo). Incluye: • Células GeneBLAzer™ M3-NFAT-bla CHO-K1 • Protocolo de ensayo GeneBLAzer™ M3-NFAT-bla CHO-K1 • Certificado de análisis Almacenamiento: Las células GeneBLAzer™ M3-NFAT-bla CHO-K1 se envían en hielo seco y deben almacenarse en nitrógeno líquido inmediatamente después de su recepción. |
|
FRET | |
Células M3-NFAT-bla CHO-K1, protocolo de ensayo M3-NFAT-bla CHO-K1, certificado de análisis | |
GeneBLAzer™ | |
BLA (betalactamasa) | |
Células en proceso de división | |
GeneBLAzer™ |
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.