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Thermo Scientific™ GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 Cells
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Marca: Thermo Scientific™ K1729
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Descripción
GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells contain the human Purinergic receptor P2, G protein-coupled, 11 (P2RY11) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of ATP. In addition, GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
P2RY11 expression is broadly distributed and has been found in the brain, pituitary, lymphocytes, spleen, intestines, macrophages, lung, stomach, adipose tissue, pancreas, kidney, prostate, heart, placenta, liver, and skeletal muscle. Differentiation of human promyelocytic HL60 cells and maturation of monocyte-derived dendritic cells have been shown to be mediated by ATP activation of P2RY11.
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Especificaciones
| NM_002566.4 | |
| Células divisoras | |
| Fluorescente | |
| P2RY11 | |
| Origen del clon unicelular | |
| 2 x 106 células | |
| P2RY11 | |
| CHO-K1 | |
| GPCR |
| Gen informador de beta lactamasa a base de células | |
| Contenido: Células K1729 GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 (El kit de carga LiveBLAzer™-FRET B⁄G, la solución D y otros materiales se solicitan por separado; consulte el protocolo). Incluye: • Células GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 • Protocolo de ensayo GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 • Certificado de análisis Almacenamiento: Las células GeneBLAzer™ P2RY11-NFAT-bla CHO-K1 se envían en hielo seco y deben almacenarse en nitrógeno líquido inmediatamente después de su recepción. |
|
| FRET | |
| Células P2RY11-NFAT-bla CHO-K1, protocolo de ensayo P2RY11-NFAT-bla CHO-K1, certificado de análisis | |
| GeneBLAzer™ | |
| BLA (betalactamasa) | |
| Células en proceso de división | |
| GeneBLAzer™ |
Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.