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HLA-DR1 Monoclonal Antibody (MEM-267), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA119393
243.34 EUR hasta el 2025-03-29
Use el código promocional "24111" para aplicar la oferta.
Alertas:
Para beneficiarse del descuento, los clientes deben comprar tres unidades del mismo producto al precio de catálogo en un solo pedido para recibir el 33.33% de descuento No hay límite para los múltiplos de 3 que los clientes pueden comprar PCODE:24111
Descripción
HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Especificaciones
| HLA-DR1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15mM sodium azide; pH 7.4 | |
| P01903, P01911 | |
| HLA-DRA, HLA-DRB1 | |
| Purified, insoluble DR1 beta chain, expressed in E. coli inclusion bodies. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Flow Cytometry, Western Blot | |
| MEM-267 | |
| Unconjugated | |
| HLA-DRA | |
| Clone P2-beta-3; DR-16; DRB1; DRw10; DW2.2/DR2.2; FLJ75017; FLJ76359; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA-DR1B; HLA-DRA; HLA-DRA1; HLA-DRB; HLA-DRB1; HLA-DRB2; human leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex, class II, DR alpha; major histocompatibility complex, class II, DR beta 1; MHC cell surface glycoprotein; MHC class II antigen; MHC class II antigen DRA; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MLRW; SS1; XXbac-BPG161M6.1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 3122, 3123 | |
| 4° C, do not freeze | |
| Liquid |
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Título del producto
HLA-DR1 Monoclonal Antibody (MEM-267), Invitrogen™ > 100 μg; Unconjugated
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