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hnRNP A1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA519431

Código de producto. 11387403

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Descripción

Descripción

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with mouse, rat and macaque monkey based on sequence homology. Store antibody at 4oC for 1-2 weeks. For long-term storage, store at -20oC.

HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.
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Produkttitel
hnRNP A1 Polyclonal Antibody, Invitrogen™ > 100 μg; Unconjugated

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