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ACROBiosystems Human ADAM8 / CD156a Protein, His Tag
Marca: ACROBiosystems AD8-H5223-50UG
Detalles adicionales : Peso : 0.00001kg
Descripción
Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
Human ADAM8, His Tag fused with a polyhistidine tag at the C-terminus, has a calculated MW of 53.8 kDa, which migrates as a 180-220 kDa band in DTT-reduced SDS-PAGE due to glycosylation. Two main fragments bands are visible with apparent MW of 69-73 kDa aEspecificaciones
AAI15405.1 | |
50 μg | |
Ile 17 - Pro 497 | |
ADAM8,MS2,CD156a | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
53.8 kDa | |
Human ADAM8, His Tag (AD8-H5223) is expressed from human 293 cells (HEK293). It contains AA Ile 17 - Pro 497 (Accession # AAI15405.1). | |
-20°C | |
ADAM8 | |
Human | |
50 mM Tris, 150 mM NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |