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Invitrogen™ Human APC15 (aa 6-69) Control Fragment Recombinant Protein

Código de producto. 30212277
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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Código de producto. 30212277

Marca: Invitrogen™ RP97313

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57736 (PA5-57736. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso P60006
Concentración ≥5.0 mg/mL
Para utilizar con (aplicación) Blocking Assay, Control
Formulación 1 M urea, PBS with no preservative; pH 7.4
ID de gen (Entrez) 25906
Nombre Human APC15 (aa 6-69) Control Fragment
Cantidad 100 μL
Estado normativo RUO
Alias de gen 3200002M19Rik; 6330414C15Rik; Anapc15; anaphase promoting complex subunit 15; anaphase prompoting complex C subunit 15; anaphase-promoting complex subunit 15; APC15; C11orf51; C15H11orf51; C21H11orf51; HSPC020; hypothetical protein LOC505356; protein HSPC020 homolog; RGD1311634; uncharacterized protein C11orf51 homolog; Unknown (protein for MGC:153425); zgc:153425
Nombre común APC15
Símbolo de gen Anapc15
Conjugado Unconjugated
Especie Human
Recombinante Recombinant
Etiqueta de proteína His-ABP-tag
Secuencia PSLFPRVTETLWFNLDRPCVEETELQQQEQQHQAWLQSIAEKDNNLVPIGKPASEHYDDEEEED
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Sistema de expresión E. coli
Formulario Liquid
Grado de pureza o calidad >80% by SDS-PAGE and Coomassie blue staining
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