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ACROBiosystems Human BCMA / TNFRSF17 Protein, Fc Tag DMF Filed
HPLC-verified
Marca: ACROBiosystems BC7-H5254-1MG
Detalles adicionales : Peso : 0.00001kg
Descripción
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.0 kDa. The protein migrates as 34-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
| NP_001183.2 | |
| 1 mg | |
| Met 1 - Ala 54 | |
| TNFRSF17,CD269,BCM,BCMA | |
| Unconjugated | |
| Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 32.0 kDa | |
| Human BCMA, Fc Tag (HPLC verified) (BC7-H5254) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # NP_001183.2). | |
| -20°C | |
| BCMA | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |