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ACROBiosystems Human CD40 / TNFRSF5 Protein, Mouse IgG2a Fc Tag, low endotoxin
MALS verified
362.89€ - 2661.24€
Especificaciones
Número de acceso | NP_001241.1 |
---|---|
Peso molecular | 46.1 kDa |
Fuente | Human CD40, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1). |
Inmunógeno | Glu 21 - Arg 193 |
Requisitos de almacenamiento | -20°C |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
15896127
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ACROBiosystems
CD0-H525A-1MG |
1 mg |
2661.24€
1 miligramo |
Fecha estimada de envío: 07-08-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
15886127
|
ACROBiosystems
CD0-H525A-100UG |
100 μg |
362.89€
100 microgramos |
Fecha estimada de envío: 07-08-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
CD40 is also known as TNFRSF5, Bp50, CDW40, MGC9013, TNFRSF5 and p50, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins, and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. CD40 contains 4 cysteine-rich repeats in the extracellular domain, and is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.1 kDa. The protein migrates as 58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
NP_001241.1 | |
Human CD40, Mouse IgG2a Fc Tag, low endotoxin (MALS verified) (CD0-H525a) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Arg 193 (Accession # P25942-1). | |
-20°C | |
CD40 | |
Human | |
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |
46.1 kDa | |
Glu 21 - Arg 193 | |
CD40,Bp50,CDW40,MGC9013,TNFRSF5,p50 | |
Unconjugated | |
Mouse IgG Fc Tag | |
Less than 0.1 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |