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Gibco™ Human IL-13 Recombinant Protein, PeproTech®
Descripción
Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Especificaciones
Especificaciones
| Número de acceso | P35225 |
| Para utilizar con (aplicación) | ELISA, Functional Assay, Western Blot |
| Formulación | protein with no preservative |
| ID de gen (Entrez) | 3596 |
| Peso molecular | 12.6 kDa |
| Nombre | Human IL-13 |
| Cantidad | 100 μg |
| Fuente | E. coli |
| Estado normativo | RUO |
| Concentración de endotoxinas | <1 EU/ μg |
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