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Gibco™ Human IL-34 Recombinant Protein, PeproTech®

Product Code. p-7246240
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Cantidad:
100 μg
10 μg
2 x 500 μg
250 μg
2 μg
500 μg
50 μg
Unit Size:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
paquete de 2
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Product Code. 17821883

Brand: Gibco™ 20034100UG

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Description

Recombinant Protein

200-34-1MG will be provided as 2 x 500 μg (200-34-500UG). Recombinant Human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Número de acceso Q6ZMJ4
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 146433
Peso molecular 52.5 kDa
Nombre Human IL-34
Método de purificación Purified
Cantidad 100 μg
Fuente HEK293 cells
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen 2010004A03Rik; AI593503; C16orf77; IL34; IL-34; ILN; Interleukin; interleukin 34; Interleukin34; interleukin-34
Nombre común IL-34
Símbolo de gen Il34
Actividad biológica Measured by its ability to induce secretion of MCP-1 from PBMCs.
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Etiqueta de proteína His-tag
Secuencia NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
Contenido y almacenamiento -20°C
Actividad Measured by its ability to induce secretion of MCP-1 from PBMCs.
Sistema de expresión HEK293 cells
Formulario Lyophilized
Grado de pureza o calidad ≥ 95% by SDS-PAGE gel and HPLC analyses.
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