missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Proteínas recombinantes
  4. Gibco™ Human Klotho Recombinant Protein, PeproTech®

Gibco™ Human Klotho Recombinant Protein, PeproTech®

Produktkod. 17801343
missing translation for 'orderingAttributeHoverText'
Cantidad:
100 μg
2 x 500 μg
20 μg
250 μg
500 μg
5 μg
Förpackningsstorlek
1 miligramo
100 microgramos
20 microgramos
250 microgramos
5 microgramos
500 microgramos
paquete de 2
Denna artikel kan inte returneras. Se returpolicy

Produktkod. 17801343

missing translation for 'mfr': Gibco™ 100535UG

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Recombinant Protein

100-53-1MG will be provided as 2 x 500 μg (100-53-500UG). Recombinant Human Klotho is a glycoprotein of 516 amino acid residues that migrates at an apparent molecular weight of 65-70 kDa by SDS-PAGE analysis under reducing conditions. Recombinant Human Klotho has a calculated molecular weight of 58.6 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifikationer

Número de acceso Q9UEF7
Para utilizar con (aplicación) Control, Western Blot Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 9365
Peso molecular 58.6 kDa
Nombre Human Klotho
Método de purificación Purified
Cantidad 5 μg
Fuente CHO cells
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen alpha-kl; HFTC3; Kl; Klotho; Klotho peptide; secreted form of Klotho protein
Nombre común Klotho
Símbolo de gen KL
Actividad biológica Determined by the dose-dependent stimulation of the proliferation of murine NIH-3T3 cells. Recombinant Human Klotho is effective in a concentration range of 0.5-2.0 ug/ml
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia EPGDGAQTWA RFSRPPAPEA AGLFQGTFPD GFLWAVGSAA YQTEGGWQQH GKGASIWDTF THHPLAPPGD SRNASLPLGA PSPLQPATGD VASDSYNNVF RDTEALRELG VTHYRFSISW ARVLPNGSAG VPNREGLRYY RRLLERLREL GVQPVVTLYH WDLPQRLQDA YGGWANRALA DHFRDYAELC FRHFGGQVKY WITIDNPYVV AWHGYATGRL APGIRGSPRL GYLVAHNLLL AHAKVWHLYN TSFRPTQGGQ VSIALSSHWI NPRRMTDHSI KECQKSLDFV LGWFAKPVFI DGDYPESMKN NLSSILPDFT ESEKKFIKGT ADFFALCFGP TLSFQLLDPH MKFRQLESPN LRQLLSWIDL EFNHPQIFIV ENGWFVSGTT KRDDAKYMYY LKKFIMETLK AIKLDGVDVI GYTAWSLMDG FEWHRGYSIR RGLFYVDFLS QDKMLLPKSS ALFYQKLIEK NGFPPLPENQ PLEGTFPCDF AWGVVDNYIQ VSQLTKPISS LTKPYH
Contenido y almacenamiento -20°C
Actividad Determined by the dose-dependent stimulation of the proliferation of murine NIH-3T3 cells. Recombinant Human Klotho is effective in a concentration range of 0.5-2.0 ug/ml.
Sistema de expresión CHO cells
Formulario Lyophilized
Grado de pureza o calidad ≥ 98% by SDS-PAGE gel and HPLC analyses.
Visa mer Visa mindre
Korrigering av produktinnehåll

Din input är viktig för oss. Fyll i det här formuläret för att ge feedback relaterad till innehållet på denna produkt.

Produkttitel

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.

Tack! Din feedback har skickats. Fisher Scientific arbetar alltid för att förbättra vårt innehåll åt dig. Vi uppskattar din feedback.