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Gibco™ Human/Mouse/Rat Activin A Recombinant Protein, PeproTech®

Código de producto. 17881223
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Cantidad:
100 μg
10 μg
2 x 500 μg
250 μg
2 μg
500 μg
50 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
paquete de 2
Código de producto. Cantidad unitSize
17881223 250 μg 250 microgramos
17851733 100 μg 100 microgramos
17800673 10 μg 10 microgramos
30087732 2 x 500 μg paquete de 2
17810113 2 x 500 μg 1 miligramo
17800113 2 μg 2 microgramos
17850453 500 μg 500 microgramos
17881363 50 μg 50 microgramos
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Código de producto. 17881223

Marca: Gibco™ 12014E250UG

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1163.20 EUR hasta el 2026-06-30
MEJOR PRECIO en promoción! Use el código promocional "27928" para aplicar la oferta.
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Descrizione

Recombinant Protein

120-14E-1MG will be provided as 2 x 500 μg (120-14E-500UG). Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
TRUSTED_SUSTAINABILITY

Specifica

Número de acceso P08476, P18331, Q04998
Para utilizar con (aplicación) Control, Bioactivity
Formulación Protein with no preservative
ID de gen (Entrez) 16323, 29200, 3624
Peso molecular 26 kDa
Nombre Human/Mouse/Rat Activin A
Método de purificación Purified
Cantidad 250 μg
Fuente E. coli
Requisitos de almacenamiento -20°C
Estado normativo RUO
Concentración de endotoxinas <1 EU/μg
Alias de gen activin A; activin beta-A chain; BMP7; BMP-7; Bone morphogenetic protein 7; EDF; Eptotermin alfa; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FRP; FSH-releasing protein; INHB; Inhba; inhibin B subunit; inhibin beta A chain; inhibin beta A protein; inhibin beta A subunit; inhibin beta-A; inhibin beta-A-subunit; inhibin beta-subunit; inhibin subunit beta A; inhibin, beta A; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1; OP1; OP-1; Osteogenic protein 1; unnamed protein product
Nombre común Activin A
Símbolo de gen Inhba
Actividad biológica The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg
Tipo de producto Protein
Conjugado Unconjugated
Recombinante Recombinant
Secuencia GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
Contenido y almacenamiento -20°C
Actividad The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
Sistema de expresión E. coli
Formulario Lyophilized
Grado de pureza o calidad ≥ 97% by SDS-PAGE gel and HPLC analyses.
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