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Gibco™ Human IL-15 Receptor alpha (soluble) Fc Recombinant Protein, PeproTech®
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Cantidad:
100 μg
1 mg
20 μg
250 μg
500 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
20 microgramos
250 microgramos
500 microgramos
Descripción
Recombinant Human sIL-15 Receptor alpha Fc has a calculated molecular weight of 44.4 kDa protein and contains 408 amino acid residues, which consists of the extracellular domain of IL-15R alpha fused to the Fc portion of human IgG. Due to glycosylation, it migrates at an apparent molecular weight of 50-60 kDa, under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Especificaciones
Especificaciones
| Número de acceso | Q13261 |
| Para utilizar con (aplicación) | Functional Assay |
| Formato | Lyophilized |
| Formulación | protein with no preservative |
| ID de gen (Entrez) | 3601 |
| Peso molecular | 44.4 kDa |
| Nombre | Human IL-15 Receptor alpha (soluble) Fc |
| Método de purificación | HPLC, SDS-PAGE |
| Cantidad | 1 mg |
| Estado normativo | RUO |
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