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Invitrogen™ Human Thyroglobulin (aa 1304-1466) Control Fragment Recombinant Protein
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Descripción
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82034 (PA5-82034. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
Especificaciones
Especificaciones
| Número de acceso | P01266 |
| Concentración | ≥5.0 mg/mL |
| Para utilizar con (aplicación) | Blocking Assay, Control |
| Formulación | 1 M urea, PBS with no preservative; pH 7.4 |
| ID de gen (Entrez) | 7038 |
| Nombre | Human Thyroglobulin (aa 1304-1466) Control Fragment |
| Cantidad | 100 μL |
| Estado normativo | RUO |
| Alias de gen | AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor |
| Nombre común | Thyroglobulin |
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