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IL12RB2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA550685
Detalles adicionales : Peso : 0.01000kg
Descripción
The antibody detects endogenous levels of total IL12RB2 protein.
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Especificaciones
| IL12RB2 | |
| Polyclonal | |
| Unconjugated | |
| IL12RB2 | |
| A930027I18Rik; Ifnm; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; Il12rb2; IL-12RB2; IL-12R-beta-2; interferon response to microorganisms; interleukin 12 receptor subunit beta 2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2; RP11-102M16.1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3595 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.5 mg/mL | |
| PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| Q99665 | |
| IL12RB2 | |
| Synthetic peptide corresponding to a region derived from internal residues of human interleukin 12 receptor, beta 2 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |