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INSIG1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA116988
369.35 EUR hasta el 2025-03-29
Use el código promocional "24111" para aplicar la oferta.
Alertas:
Para beneficiarse del descuento, los clientes deben comprar tres unidades del mismo producto al precio de catálogo en un solo pedido para recibir el 33.33% de descuento No hay límite para los múltiplos de 3 que los clientes pueden comprar PCODE:24111
Descripción
This antibody does not cross-react with Insig2. Suggested positive control: HepG2 lysate, antigen standard for INSIG1 (transient overexpression lysate).
Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Especificaciones
| INSIG1 | |
| Polyclonal | |
| Unconjugated | |
| INSIG1 | |
| 1810013C12Rik; CL6; CL-6; fb55a03; fi35b10; growth response protein (CL-6); immediate-early protein CL-6; INSIG1; INSIG-1; INSIG-1 membrane protein; insulin induced gene 1; insulin induced protein 1; insulin-induced gene 1 protein; Insulin-induced growth response protein CL-6; MGC1405; wu:fb55a03; wu:fi35b10; zgc:55439 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3638, 64194 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 1.02 mg/mL | |
| PBS with 30% glycerol and 0.1% sodium azide | |
| O15503, Q08755 | |
| INSIG1 | |
| Synthetic peptide corresponding to a region between residues 1-100 of human Insig1 | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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Título del producto
INSIG1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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