missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ IRF8 Monoclonal Antibody (ZI003)
Mouse Monoclonal Antibody
Marca: Invitrogen™ 398800
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
IRF8 Monoclonal Antibody for Western Blot, ELISA
IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.
Especificaciones
| IRF8 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| P23611, Q02556 | |
| Irf8 | |
| Synthetic peptide derived from the C-terminal region of the human ICSBP protein. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 κ |
| ELISA, Western Blot | |
| ZI003 | |
| Unconjugated | |
| Irf8 | |
| AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP | |
| Mouse | |
| Protein A | |
| RUO | |
| 15900, 3394 | |
| -20°C | |
| Liquid |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido